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Conquering death will be humanity’s greatest achievement.

706 following962k followers

The Entertainer

Bryan Johnson, also known as 'dd', is a charismatic online personality who thrives on engagement and spectacle. With a playful approach to social media, he loves to keep his audience entertained and guessing. His profile suggests a flair for the dramatic and a willingness to share personal moments for public consumption.

Impressions
29.3M-2.7M
$5505.90
Likes
312.9k-29.5k
74%
Retweets
13.3k-1.8k
3%
Replies
25.9k-2.4k
6%
Bookmarks
68.5k-9.6k
16%

Bryan's laptop is the most anticipated sequel since 'Game of Thrones', too bad it's probably just cat videos.

Successfully turned a personal challenge into a victory by winning a legal battle and using it as a platform to share his story and strengthen his personal brand.

To captivate and amuse his audience while also pushing the boundaries of conventional online behavior.

Values humor, transparency, and the power of personal branding. Believes in the importance of staying true to oneself, even if it means being vulnerable in the public eye.

His ability to connect with people through humor and relatable content makes him highly engaging and popular among his followers.

His approach can sometimes be perceived as too eccentric or controversial, potentially alienating some audiences or attracting unwanted attention.

To maintain and grow his audience, Bryan should continue to leverage his unique voice and experiences, while also being mindful of the fine line between entertaining and oversharing. Diversifying his content to include more in-depth insights into his life and interests could also attract a broader audience.

Known for his quirky sense of humor and unexpected antics, such as teasing about content on his laptop and sharing humorous interactions with others.

Top tweets of Bryan Johnson

Guys…I have a girlfriend. Now I know what you’re thinking…how is it possible that anyone would want to be with me? I understand where you’re coming from. I think the answer is: her puzzle piece fits mine. In my early twenties, I read the biography of the American founding father John Adams. He and his wife Abigail had one of the great partnerships in American history; intellectually matched, emotionally intertwined, and co-architects of something bigger than themselves. I wanted what they had. But it wasn’t within reach. Years before, I’d married in a sort of arranged Mormon marriage. Unsure how else to explain it. We were functional, but we weren’t John and Abigail. We split after thirteen years. At age 34, after selling Braintree Venmo, and emerging from a mismatched marriage and the repression of Mormonism, I set out to rebuild myself and find partnership.  I met a woman in LA who became my first-ever girlfriend. Coming from a sheltered background, I was blind to the obvious warnings. I was dangerously naive. That relationship unraveled and was followed by litigation. The experience was unnerving and left me wondering if I could ever trust again. By the time I was 44, I started reconciling with the possibility of a life without partnership. @_katetolo and I met at my brain interface company Kernel. She’d discovered my work using neurotechnology to improve human well-being and merge human and AI. Even though she’d been dreaming of a career in fashion, she was drawn to what she foresaw as the defining question of our time: how will humans successfully co-evolve with AI. We shared the same obsession. The puzzle piece fit was immediate, as immediate as either of us had ever experienced. Yet we maintained our professional boundaries. When we worked on our first project together, the back and forth was effortless. She could conceptualize and feel what I couldn’t and vice versa. It helped that both Kate and I had a natural disposition towards hard work. Our joy came from creation. Kate was luminescent. When I saw her about the office, butterflies fluttered in my stomach.  Each day she’d show up wearing some unexpected combination of colors, textures, styles and accessories. Always tasteful, playful and interesting. She didn’t chase fancy brands. Most of her clothing was from the thrift store. It wasn’t how she looked but how her mind worked: original, eccentric, entirely her own. She was art. We both worked very hard and valued every second of the day.  One evening around 6:30 pm she dropped by my office and we talked for hours. It had been all business before.  This was the first time we stepped into each other’s personal lives. My heart strings pulled but my brain pushed back. ‘We know we can’t trust again’, my mind firmly stated. Our after-hours meet-ups in my office became a daily ritual. The favorite part of my day. We’d reminisce about work and tiptoe a bit deeper each time into each other’s personal lives. I’d recently started my new anti-aging project and one night Kate suggested to me that I should put the entire thing online to allow others to follow on. We worked together to put up a website and got a v1 out. We pondered what to call it, and decided on ‘Project Blueprint’. We were oddly from entirely different worlds but somehow the same person. Yet neither of us dared take the next step. We didn’t want to imperil our work relationship and we remained deeply skeptical of each other.  The combination of Kate being raised to distrust all things and me still feeling the sting of the previous relationship left us stirring in a pot of anticipatory disaster. Before long, whether we liked it or not, we’d become each other's favorite person. We’d spend every moment we could together. Social events and the weekends were still off-limits as our relationship was professional. We were both secretly wondering, ‘does the other person feel what I’m feeling?’ Unable to withstand any longer, after a year and a half of unspoken affection, one night I softly floated the balloon of inquiry. She confirmed it was reciprocal. Still, with things being so new, neither of us wanted to make our relationship public. We needed time to stabilize, mature and assess whether this was short or long term. I’m a 48 year old American, raised Mormon, with three children. She’s a 30 year old Bosnian-Australian-American. It took time to bridge our worlds. In our years of knowing each other, three of them have been navigating a relationship. All while building a business and movement. There have been many times where we didn’t know if we’d make it. In the last year, we’ve found our flow.  I trust Kate as much as my mother. She knows how to scaffold trust. She anticipates your anticipation and knows your reaction before you react. She’s meticulous in the integrity of our relationship. She’s even been pivotal in helping my father and me reconcile and navigate the contours of our relationship. In the past few years, Blueprint and Don’t Die have become global phenomena. Kate is the unsung hero.  She and I have been stride on stride since inception. She’s proven an exceptional executor and despite her unconventional background, intuitively knows things. Her creativity keeps me forever guessing what she’ll say or come up with next. Our minds have become so intertwined that life feels naked without her. Her story warrants being told as others will be better off emulating her practices and abilities. What I find most impressive about Kate is her prescience and thoughtfulness. She sees forwards, backwards, and side to side. Relative to her, I feel myopic in my awareness of the world. She can see through others, as an x-ray would. She then structures all that information and can package it in simple, understandable terms. In ways that allow for everyone to win. Kate is soft spoken, self-deprecating and understated. These attributes cloak her ferocious ambition, piercing intellect, and delightful creativity. Give her five minutes and she will reframe your world. But most people don’t know to look. They assume she’s my assistant. It’s such a loss because people are looking for what she has to offer. My son Talmage, Kate, and I are family. Nothing makes us happier than being together. Our conversations are fast, dark, and rowdy. Family feeds the soul, and we are nourished. As my son considers possible partners, he wisely models them off of Kate. Deep companionship is a universal human want.  And while there are eight billion of us on this planet, most struggle to achieve it, including those in relationships. It’s the most fulfilling of human experiences and also the most elusive. The joy of being seen, appreciated and loved, and offering the same to another. I wrote dozens of different sentences trying to capture what the want and struggle for deep companionship feels like. I deleted them all as none could holistically capture the emotional architecture of it. Then one day while exercising, I realized what it feels like: what the explorer Ernest Shackleton and his crew must have felt returning to land after being shipwrecked and surviving 497 days adrift in brutal Antarctic. It’s a bit of a dramatic comparison, however, I suspect many of you can relate. Kate feels like land to me after being adrift and searching for 25 years. Life sinks or sails based upon the quality of our most intimate relationships. No amount of professional success can plug the sinking hole of an acrimonious personal relationship. At this point, Kate and I have nearly become one person. We have entire conversations with a single look, sound, gesture or image. We independently come up with the same ideas and insights, suggesting to me that maybe it’s our tandem effort generating them. Our relationship is stable, positive, and calm. I’ve wanted this my entire life and impatiently waited 25 years for it to arrive. It’s better than anything I imagined. Lucky me, I found my Abigail Adams.

17M

On @netflix Jan 1 2025 is the year of don’t die

9M

Most engaged tweets of Bryan Johnson

Nighttime erection data from my 19-year-old son, @talmagejohnson_, and me. His duration is two minutes longer than mine. Raise children to stand tall, be firm, and be upright.

34M

It’s been 19 days and 20 hrs since I last felt Kate’s warm embrace. She landed 47 minutes ago. The 24 hours of travel no doubt has her rushing to shower. She needs to cleanse herself of a dirtied world incompatible with her sensibilities. The wash doubles as a ritual, preparatory for entrance into the symbolic world we’ve constructed. The time apart has been costly.  My body’s electrical signaling betrays the separation. Without her touch, my vagus nerve’s 100,000 myelinated fibers have dropped their high frequency spectral power, squawking distress. An intelligent system broadcasting diminished wave forms, hoping to be heard.  There are other signals of distress. My white blood cells have shifted their gene expression, upregulating pro-inflammatory genes IL-6 and TNF-alpha and downregulating my antiviral genes.  A pro-aging biochemical signature of a system suffering hardship. My environment is a pristine anti-aging laboratory. Air, water, food and light are meticulously measured. Toxins are filtered. Purification systems run autonomously. Biomarkers tracked. Nutrition is calibrated. Yet outside my control is the affection of another. The 68 trillion cells that constitute Bryan Johnson run non-negotiable code. They demand tenderness, and not of a whimsical type, but deep, all-encompassing love that must be earned and carefully maintained. Otherwise they protest in self-termination. She’s now only 13 miles away and I can viscerally feel her essence. The transmission pulses in high fidelity. As if there were a fiber optic cable streaming our connection at light speed through the multiplexed cylinders of glass. The time apart created latency, buffering the connection, depriving us of the luminescence and dimming into noise. In 15 minutes she will be within reach. I can visualize the whites of her eyes and smell her aroma. When she arrives, she will be shy. Whenever we are apart, she returns to zero. Her previous openness will be closed. Her emotional dynamic range will be held in reserve until she feels she is safe and can trust.  I’ll need to kindle her again. The rush of the courtship enthralls me. The anticipation drives a small cluster of my midbrain neurons to flood dopamine. Nerve fibers activate, lighting up my skin’s receptors as it awaits for slow, caressing touch. My hypothalamus begins synthesizing oxytocin, preparing to dump it upon first eye contact to ensure the reestablishment of our pair bond. This biochemical orchestra fills me with delight and sensorial want. Kate’s been mulling over what she’ll wear for days.  She’s considered dozens of possibilities and modeled out my anticipated emotional state, the weather, and our planned activities. The colors will be representative of her psychological state and be positioned to soothe mine. The texture, style, and hues will interplay with our biology. The deliberately chosen accessories will add flair, intrigue and play. This is how she flirts, seduces and bypasses my mind to speak directly to my physiology. She has other tricks too. She’s arrived. I must wait for her. Her timidness will want to determine the cadence. I hear the door crack open and her bag drop to the floor. She’s nervous. I’m on the couch, neutral and open. She rounds the corner and our eyes meet. The inhibitions wither as the magnetism draws us together. Soft hellos are whispered and our bodies interdigitate. I feel her finger tips on the back of my neck. Goose bumps light up my body. Skin nerve cells fire signals directly to my brain, bypassing the analytical mind. The hypothalamus dumps the oxytocin, inhibiting fear and lowering cortisol. The body washes itself in this anti-inflammatory chain reaction.  Our respiration and heart beats are now synchronizing. The brain piles on with a release of endorphins to soothe the psychological pain of our separation. New powers are now in control. Let them run in glory. I press my cheek against hers. The skin on skin triggers a wave of desire. I brush her lips with mine, catalyzing a massive activation of neurons in her brain, overwhelming thought and forcing presence. She relents and wants to dance. She’s home. I slip my hand under her shirt and brush the small of her back. Goosebumps spread like a wildfire across her body. Her hypothalamus stimulates the release of GnRH which tells the pituitary gland to wake up her reproductive system. Our olfactory systems consume each other with delight, signaling immune system compatibility. I move both my hands to her jawline, holding her head firmly in place. Our mirror neurons speak to each other. I know what she wants. My lips press against hers and I softly bite her lower lip. Kate’s blood vessels dilate from the acetylcholine and nitric oxide release, flushing her lips, skin and body. The cascade is nearing waterfall. The executive control of our brains surrenders. No longer concerned with the 68 trillion cells. The prefrontal cortex goes dark. Eliminating future planning and probabilistic modeling. Activity in our parietal lobes diminishes, dissolving the boundary that distinguishes between self and other. No longer is there Kate and Bryan, just a singular biological entity suspended in a state of bliss. The outside world goes quiet. It doesn’t exist. We dissolve into raw existence.

20M

Guys…I have a girlfriend. Now I know what you’re thinking…how is it possible that anyone would want to be with me? I understand where you’re coming from. I think the answer is: her puzzle piece fits mine. In my early twenties, I read the biography of the American founding father John Adams. He and his wife Abigail had one of the great partnerships in American history; intellectually matched, emotionally intertwined, and co-architects of something bigger than themselves. I wanted what they had. But it wasn’t within reach. Years before, I’d married in a sort of arranged Mormon marriage. Unsure how else to explain it. We were functional, but we weren’t John and Abigail. We split after thirteen years. At age 34, after selling Braintree Venmo, and emerging from a mismatched marriage and the repression of Mormonism, I set out to rebuild myself and find partnership.  I met a woman in LA who became my first-ever girlfriend. Coming from a sheltered background, I was blind to the obvious warnings. I was dangerously naive. That relationship unraveled and was followed by litigation. The experience was unnerving and left me wondering if I could ever trust again. By the time I was 44, I started reconciling with the possibility of a life without partnership. @_katetolo and I met at my brain interface company Kernel. She’d discovered my work using neurotechnology to improve human well-being and merge human and AI. Even though she’d been dreaming of a career in fashion, she was drawn to what she foresaw as the defining question of our time: how will humans successfully co-evolve with AI. We shared the same obsession. The puzzle piece fit was immediate, as immediate as either of us had ever experienced. Yet we maintained our professional boundaries. When we worked on our first project together, the back and forth was effortless. She could conceptualize and feel what I couldn’t and vice versa. It helped that both Kate and I had a natural disposition towards hard work. Our joy came from creation. Kate was luminescent. When I saw her about the office, butterflies fluttered in my stomach.  Each day she’d show up wearing some unexpected combination of colors, textures, styles and accessories. Always tasteful, playful and interesting. She didn’t chase fancy brands. Most of her clothing was from the thrift store. It wasn’t how she looked but how her mind worked: original, eccentric, entirely her own. She was art. We both worked very hard and valued every second of the day.  One evening around 6:30 pm she dropped by my office and we talked for hours. It had been all business before.  This was the first time we stepped into each other’s personal lives. My heart strings pulled but my brain pushed back. ‘We know we can’t trust again’, my mind firmly stated. Our after-hours meet-ups in my office became a daily ritual. The favorite part of my day. We’d reminisce about work and tiptoe a bit deeper each time into each other’s personal lives. I’d recently started my new anti-aging project and one night Kate suggested to me that I should put the entire thing online to allow others to follow on. We worked together to put up a website and got a v1 out. We pondered what to call it, and decided on ‘Project Blueprint’. We were oddly from entirely different worlds but somehow the same person. Yet neither of us dared take the next step. We didn’t want to imperil our work relationship and we remained deeply skeptical of each other.  The combination of Kate being raised to distrust all things and me still feeling the sting of the previous relationship left us stirring in a pot of anticipatory disaster. Before long, whether we liked it or not, we’d become each other's favorite person. We’d spend every moment we could together. Social events and the weekends were still off-limits as our relationship was professional. We were both secretly wondering, ‘does the other person feel what I’m feeling?’ Unable to withstand any longer, after a year and a half of unspoken affection, one night I softly floated the balloon of inquiry. She confirmed it was reciprocal. Still, with things being so new, neither of us wanted to make our relationship public. We needed time to stabilize, mature and assess whether this was short or long term. I’m a 48 year old American, raised Mormon, with three children. She’s a 30 year old Bosnian-Australian-American. It took time to bridge our worlds. In our years of knowing each other, three of them have been navigating a relationship. All while building a business and movement. There have been many times where we didn’t know if we’d make it. In the last year, we’ve found our flow.  I trust Kate as much as my mother. She knows how to scaffold trust. She anticipates your anticipation and knows your reaction before you react. She’s meticulous in the integrity of our relationship. She’s even been pivotal in helping my father and me reconcile and navigate the contours of our relationship. In the past few years, Blueprint and Don’t Die have become global phenomena. Kate is the unsung hero.  She and I have been stride on stride since inception. She’s proven an exceptional executor and despite her unconventional background, intuitively knows things. Her creativity keeps me forever guessing what she’ll say or come up with next. Our minds have become so intertwined that life feels naked without her. Her story warrants being told as others will be better off emulating her practices and abilities. What I find most impressive about Kate is her prescience and thoughtfulness. She sees forwards, backwards, and side to side. Relative to her, I feel myopic in my awareness of the world. She can see through others, as an x-ray would. She then structures all that information and can package it in simple, understandable terms. In ways that allow for everyone to win. Kate is soft spoken, self-deprecating and understated. These attributes cloak her ferocious ambition, piercing intellect, and delightful creativity. Give her five minutes and she will reframe your world. But most people don’t know to look. They assume she’s my assistant. It’s such a loss because people are looking for what she has to offer. My son Talmage, Kate, and I are family. Nothing makes us happier than being together. Our conversations are fast, dark, and rowdy. Family feeds the soul, and we are nourished. As my son considers possible partners, he wisely models them off of Kate. Deep companionship is a universal human want.  And while there are eight billion of us on this planet, most struggle to achieve it, including those in relationships. It’s the most fulfilling of human experiences and also the most elusive. The joy of being seen, appreciated and loved, and offering the same to another. I wrote dozens of different sentences trying to capture what the want and struggle for deep companionship feels like. I deleted them all as none could holistically capture the emotional architecture of it. Then one day while exercising, I realized what it feels like: what the explorer Ernest Shackleton and his crew must have felt returning to land after being shipwrecked and surviving 497 days adrift in brutal Antarctic. It’s a bit of a dramatic comparison, however, I suspect many of you can relate. Kate feels like land to me after being adrift and searching for 25 years. Life sinks or sails based upon the quality of our most intimate relationships. No amount of professional success can plug the sinking hole of an acrimonious personal relationship. At this point, Kate and I have nearly become one person. We have entire conversations with a single look, sound, gesture or image. We independently come up with the same ideas and insights, suggesting to me that maybe it’s our tandem effort generating them. Our relationship is stable, positive, and calm. I’ve wanted this my entire life and impatiently waited 25 years for it to arrive. It’s better than anything I imagined. Lucky me, I found my Abigail Adams.

17M

Doing magic mushrooms this Sunday. Protocol + dose: 5 grams + frequency: 1x/mo for 3 mo + objective: exploring longevity effects Measurement + 249 independent biomarkers + 29 vials of blood + brain scans + urine, stool, saliva, fertility + multi-omics profiling (DNA, epigenetics, metabolism, hormones, microbiome, proteins, cognition) Cardiovascular + LDL-C + HDL-C + Triglycerides + Total cholesterol + Apolipoprotein B + Apolipoprotein A-1 + Lipoprotein(a) + LDL-P + HDL-P + Small LDL-P + LDL size + Large VLDL-P + Large HDL-P + VLDL size + HDL size + LP-IR score + Oxidized LDL + Lp-PLA2 activity + Myeloperoxidase (MPO) + Homocysteine + VEGF Hematology + WBC + RBC + Hemoglobin + Hematocrit + MCV + MCH + MCHC + RDW + Platelets + Neutrophils + Lymphocytes + Monocytes + Eosinophils + Basophils + Immature granulocytes + Erythropoietin (EPO) + ABO/Rh typing Hormonal + Thyroid panel with TSH + Free T4 + Testosterone + Dihydrotestosterone (DHT) + 5α-DHT + Prolactin + Estradiol + LH + FSH + Estrone (E1) + Estriol (E3) + Androstenedione + Androsterone + 5β-Androstanediol + Etiocholanolone + Cortisol + Cortisone + DHEA + DHEA-S + Pregnenolone + IGF-1 + Melatonin (6-hydroxymelatonin sulfate) Metabolic + Glucose + Insulin + Hemoglobin A1c + α-Hydroxybutyrate + β-Hydroxybutyrate + Uric acid Kidney + BUN + Creatinine + eGFR + BUN/Creatinine ratio + Cystatin C + Urinalysis (specific gravity, pH, color, appearance, leukocyte esterase, protein, glucose, ketones, occult blood, bilirubin, urobilinogen, nitrite, WBC [hpf], RBC [hpf], epithelial cells, casts, bacteria) + Albumin/Creatinine ratio Pancreatic + Total protein + Albumin + Globulin + Total bilirubin + Alkaline phosphatase + AST + ALT + GGT + Amylase + Lipase Minerals + Sodium + Potassium + Chloride + CO₂ (bicarbonate) + Calcium + Magnesium + Iron + TIBC + UIBC + Iron saturation + Ferritin + Zinc Vitamins + Vitamin B12 + 25-hydroxy Vitamin D + Coenzyme Q10 + α-Tocopherol + β-Carotene + Glutathione + Total glutathione Amino Acids + Cysteine + Methionine + Taurine + Glycine + Serine + Threonine + Alanine + Valine + Leucine + Isoleucine + Phenylalanine + Tyrosine + Tryptophan Inflammation + Interleukin-6 (IL-6) + Interleukin-10 (IL-10) + Tumor Necrosis Factor-α (TNF-α) + Rheumatoid factor (RF) + ANA by IFA + Calprotectin (GI inflammation), + Secretory IgA (mucosal immunity) Neurology + P-tau217 + Epinephrine metabolites (metanephrine, normetanephrine) + Homovanillate (HVA) + Vanilmandelate (VMA) + 5-Hydroxyindoleacetate (5-HIAA) Toxicology + Lead + Lithium Urology + PSA total Fertility + Total Motile Count + Sample Volume + Concentration + Motility + Morphology + Count Metabolomics + Citrate + cis-Aconitate + Isocitrate + α-Ketoglutarate + Succinate + Fumarate + Malate + Pyruvate + Lactate + 2-Hydroxyglutarate, + Hydroxymethylglutarate, + 3-Methylglutaconate, + 2-Methylsuccinate + Formiminoglutamate (FIGLU), + Methylmalonate (MMA), + Xanthurenate + Kynurenate, + Quinolinic acid + Glucarate, + 8-Hydroxy-2′-deoxyguanosine (8-OHdG), + Pyroglutamate + 3-Hydroxyphenylacetate, + 4-Hydroxyphenylacetate, + 2-Hydroxyphenylacetic acid + 4-Cresol, + p-Hydroxybenzoate, + Benzoate, + Hippurate/Hippuric acid + Phenylacetate/Phenylacetic acid, + Indoleacetate/Indoleacetic acid + Arabinose, + Citramalic acid, + α-Hydroxyisobutyric acid Microbiome + Bacteroides fragilis + Bacteroides vulgatus + Faecalibacterium prausnitzii + Akkermansia muciniphila + Roseburia spp. + Eubacterium rectale + Lactobacillus spp. + Bifidobacterium spp. + Escherichia coli + Clostridium difficile + Enterococcus faecalis + Candida albicans + Saccharomyces boulardii + Prevotella copri + Ruminococcus spp. + Methanobrevibacter smithii + Blautia spp. + Proteobacteria spp. + Firmicutes/Bacteroidetes ratio + Beta-glucuronidase + Butyrate + Propionate + Acetate Aging & Epigenetics + Telomere length + Relative telomerase activity + DNA methylation age + DNA methylation levels at CpG sites associated with biological aging + Glucocorticoid receptor methylation (NR3C1) + SIRT1 methylation + MTOR methylation + Oxidative stress response genes (NFE2L2 promoter methylation) Cognitive + Brain age score + Functional connectivity strength + Global connectivity index + Hemodynamic response amplitude + Hemodynamic response latency + Resting-state oxygenated hemoglobin (HbO) concentration + Resting-state deoxygenated hemoglobin (HbR) concentration + Total hemoglobin (HbT) concentration + Oxygen saturation (O₂Sat) + Cerebral blood volume (CBV) + Cerebral blood flow (CBF) + Neurovascular coupling index + Prefrontal cortex oxygenation + Parietal cortex oxygenation + Temporal cortex oxygenation + Occipital cortex oxygenation + Task-evoked hemodynamic response (HbO/HbR) + Temporal autocorrelation of hemodynamics + Functional brain network modularity + Inter-regional coherence + Brain lateralization index + Oscillatory power (slow cortical fluctuations) + Phase synchronization index + Mean reaction time (during cognitive tasks) + Reaction time variability + Heart-rate variability (HRV) + Resting heart rate

18M

I’m going to try and achieve immortality by 2039. One year of time passes and I remain the same biological age. I invite you to join me. The search for the fountain of youth is the oldest story ever told. It’s been the dream of dreamers for millennia but always painfully out of reach. For the first time in the history of life on earth, in just the past 24 months, the window has opened for a conscious being to realistically strive for this goal. It is an absolutely insane moment. We currently do not know how 2039 immortality will be achieved. There are new, promising therapies that can turn back the clock decades, but they’re buggy. Sometimes they mistakenly cause cancer. We gotta fix that. But we know immortality is possible because nature has already solved it. This isn’t a physics problem like trying to travel faster than the speed of light, it’s a biological engineering problem that evolution has cracked multiple times. The freshwater hydra constantly regenerates its own cells and doesn’t succumb to senescence. It is effectively ageless. The "immortal jellyfish" (Turritopsis dohrnii) can revert its cells back to a youthful state and restart its life cycle indefinitely. Lobsters produce an especially active form of an enzyme called telomerase that preserves their telomeres and keeps their DNA from degrading as they age. We need to port the software to humans. 2039 is a reasonable target because of the accelerated, AI-driven rate of innovation. AI is morphing from assistant to scientist.  It is powering current researchers with previously unimagined capabilities to enhance discovery and development. That, coupled with enhanced biomarker measurement, creates a closed-loop system of improvement that will speed things up dramatically. This is what I’ve been doing for six years. As crude as longevity technology is today, the improvements I’ve personally seen are stunning. I started as a worn-down, inflamed, aged 42 year old who’d broken himself on the rocks of American food slop and entrepreneurship martyrdom. Six years later, my body largely operates at elite 18 year old levels. That includes my cardiovascular system, fertility, strength, and hormones. Not all is well though. I have mild to moderate hearing loss in my left ear that we can’t fix and my brain is anatomically age 42 (I’m 48). Still, unreal results. My team and I did this by following the scientific method. We measured the biological age of every organ. We referenced the best scientific evidence on how to slow aging and rejuvenate.  We methodically completed these protocols and measured again. Rinse and repeat. We could do so much more and faster if we had better measurement and better therapies. Both of which are cooking all over the world right now. To speed things up now, I’m currently having thousands of Bryan Johnson organ clones built in a dish. This will allow me to test drugs and other molecules against my biology to accelerate learning and save my body from potential mishaps. Yes, we’ll make mistakes. Hopefully they won’t be fatal. And of course there’s always bad luck to contend with. But I trust in fate and I believe that destiny is going to grant the human race the pleasure of achieving the ultimate: immortality. While immortality would certainly be cool, the real (secret) objective is to focus our collective attention on a positive goal. Something that helps us feel hope and excitement for the future. I personally love the idea of having a child-like mind, 18-year-old physical vibrancy, and a lifetime of wisdom. This 2039 goal is as much about AI as it is about us humans. It’s about how we survive giving birth to superintelligence. It’s kind of a big deal. We haven’t done it before. A lot can go wrong. I figure that one of the best ways to improve the probability that we build safe AI, and don’t kill each other in the meantime, is to transform our shared aspirations from yolo to don’t die. Right now, we are a suicidal species. We do all kinds of really primitive shit. We unnecessarily kill ourselves with what we eat and how we live our lives. Companies make profits from killing other people with their products. We trash the only home we have. We celebrate these things as virtue.  It’s really fucked up and backward. Soon enough we’ll realize just how infantile we are right now. The 2039 goal points us in the right direction. To say yes to life and no to death. Defiance even. If you’re interested in doing this with me, I’ll continue to share everything I do for free. I’m also going to build this out in Blueprint. We’ll help you do exactly what I’m doing, at a fraction of the cost and effort, alongside an aligned and motivated community. I think this is the coolest goal imaginable. I find it hard to believe that of all the people who’ve lived, it’s us who get the opportunity to have this moment. I pray that we have the courage to appreciate the sacredness of our existence. I pray that we will be brave enough to defend her amidst the onslaught of all the forces that would try to end her. We don’t know, but we may be the only intelligent life to exist in our corner of the galaxy. I pray we will be warriors, caretakers and stewards of existence and honor the gift that has been bestowed on us.

6M

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Dan Katz. Chicago @barstoolsports. Email - chicagotips@barstoolsports. @PardonMyTake podcast w/ @PFTCommenter. RT not endorsement

4k following1M followers
The Entertainer
@levie

ceo @box - your business lives in content. unleash it with AI

780 following2M followers
The Entertainer
@ishmilly

Founder at DomainerEXPO. Domain Names Investor. Founder at Prediction Conference

4k following12k followers

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